Journal article
Real-world experience of metformin use in pregnancy: Observational data from the Northern Territory Diabetes in Pregnancy Clinical Register
LJ Maple-Brown, G Lindenmayer, F Barzi, C Whitbread, C Connors, E Moore, J Boyle, M Kirkwood, IL Lee, D Longmore, P van Dokkum, M Wicks, M Dowden, C Inglis, M Cotter, R Kirkham, S Corpus, S Chitturi, S Thomas, K O'Dea Show all
Journal of Diabetes | WILEY | Published : 2019
Abstract
Background: In Australia's Northern Territory, Indigenous mothers account for 33% of births and have high rates of hyperglycemia in pregnancy. The prevalence of type 2 diabetes (T2D) in pregnancy is up to 10-fold higher in Indigenous than non-Indigenous Australian mothers, and the use of metformin is common. We assessed birth outcomes in relation to metformin use during pregnancy from a clinical register. Methods: The study included women with gestational diabetes (GDM), newly diagnosed diabetes in pregnancy (DIP), or pre-existing T2D from 2012 to 2016. Data were analyzed for metformin use in the third trimester. Regression models were adjusted for maternal age, body mass index, parity, and ..
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Grants
Awarded by National Health and Medical Research Council
Funding Acknowledgements
The Northern Territory Diabetes in Pregnancy Partnership is funded by an Australian National Health and Medical Research Council (NHMRC) Partnership Project Grant (1032116), with additional support from NHMRC Program Grant 631974 and Global Alliance Chronic Disease NHMRC Grant 1092968. LM-B is supported by an NHMRC Practitioner Fellowship (1078477). The views expressed in this publication are those of the authors and do not reflect the views of the NHMRC. The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript.